HArmonyCa®

HArmonyCa® is a first-of-its-kind "hybrid" biostimulator by Allergan, combining hyaluronic acid (HA) for immediate volume, and ‘lift’ with calcium hydroxyapatite (CaHA) from the stimulation of new collagen. 

It may be used to address sagging skin, deep lines (like smile or marionette lines), and loss of definition in areas such as the cheek or jawline.

HArmonyCa® was launched by Allergan Aesthetics in April 2022. The product entered the European and select EEMEA (Eastern Europe, Middle East, and Africa) markets at the Aesthetic & Anti-Aging Medicine World Congress (AMWC) in Monaco. Allergan had previously acquired the company that developed the product, Luminera, in October 2020. 

HArmonyCa® is considered an innovative, "first-in-class" treatment because it combines two active compounds in a single injection: hyaluronic acid (HA) for immediate lift and volume, and calcium hydroxyapatite (CaHA) microspheres for longer-term collagen stimulation. 

HArmonyCa® received Health Canada approval as a Class 3 Device in 2026 (License no. 114447, 2025-12-05). It is now available across the country. 

While both may be considered "biostimulators," they are not the same. HArmonyCa® is a hybrid filler that contains hyaluronic acid for instant mid facial volume and calcium hydroxyapatite for collagen stimulation.

Many dermal fillers rely solely on hyaluronic acid (HA) to provide volume and/or hydration, however HArmonyCa® combines HA with calcium hydroxyapatite. This hybrid formula allows HArmonyCa® to provide immediate volume while also stimulating longer-term collagen production.

Patients can be treated with HArmonyCa® at the same time as Juvéderm® fillers, SkinVive™, or even Botox® (when clinically appropriate). 

The way we think about it is that SkinVive™ provides hydration, Juvéderm® changes facial structure, and HArmonyCa® creates lift with improved skin architecture.

Full effects typically take about 1 month and then last 12-18 months. Because HArmonyCa® is a sort of 'hybrid' filler, as the HA slowly dissipates, the collagen production from CaHA should help maintain structure.

HArmonyCa® is injected in the subdermis/subcutaneous areas of the cheeks, jawline, and lower face, including near the ear and hairline. 

It should never be injected into the glabella (frown lines), perioral/lip, or periocular region (eyes).

Using a cannula to create lift, volume, and skin tightening, HA provides immediate volume while the CaHA stimulates long-term collagen formation for maintenance. This may improve areas like the zygomatic arch (cheekbones) and mandibular body to address sagging and deep lines, offering a natural lift and improved skin quality. 

The "C Approach" requires 2 syringes of HArmonyCa® and costs $1950 for the treatment ($975/syringe).

The "C Plus Approach" requires 3 syringes of HArmonyCa® and costs $2775 for the treatment ($925/syringe). 

5% GST + 2.65% Square Reader fee are added to this. 

There are no consultation or follow up fees. Please review the Informed Consent sheet carefully. No refunds or complimentary re-treatments are given regardless of cosmetic or medical outcome. 

We do not offer treatment with only 1 syringe (or half syringes) . 

All medical procedures carry risk.  Please review the Informed Consent sheet carefully and speak with the treating physician. 

Give us a call at 778-265-1377 ex. 1. 

If you are looking for a complimentary consultation only, let us know and we will book you in for 15 minutes. Otherwise, appointments are 45 minutes which includes treatment time. 

Please print, review and sign the Informed Consent sheet prior to your appointment. Bring this with you to the clinic. 

At the Nanaimo Botox® Clinic, currently Drs. Ward and J. Wright perform this procedure. 

Fairly minimal for both but please review the Informed Consent sheet and the following document on aftercare. 

See the following from Allergan: https://www.allerganaesthetics.gr/en/our-brands/harmonyca